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Noticeable changes to the auditory, visual, and tactile senses may become apparent around 30 minutes to an hour after ingestion, although effects may take up to two hours to take place.These shifts in perception visually include enhancement and contrasting of colors, strange light phenomena (such as auras or "halos" around light sources), increased visual acuity, surfaces that seem to ripple, shimmer, or breathe; complex open and closed eye visuals of form constants or images, objects that warp, morph, or change solid colours; a sense of melting into the environment, and trails behind moving objects.They are possibly depicted in Stone Age rock art in Europe and Africa, and have a history of use in pre-Columbian Mesoamerica.Some cultures have used these mushrooms in their religious rites and ceremonies.Mushroom stones and motifs have been found in Guatemala. A Psilocybe species was known to the Aztecs as teōnanācatl (literally "divine mushroom" - agglutinative form of teōtl (god, sacred) and nanācatl (mushroom) in Náhuatl) and were reportedly served at the coronation of the Aztec ruler Moctezuma II in 1502.Aztecs and Mazatecs referred to psilocybin mushrooms as genius mushrooms, divinatory mushrooms, and wondrous mushrooms, when translated into English.
It has been argued that prehistoric rock art near Villar del Humo, Spain, offers evidence that Psilocybe hispanica was used in religious rituals 6,000 years ago, Hallucinogenic species of the Psilocybe genus have a history of use among the native peoples of Mesoamerica for religious communion, divination, and healing, from pre-Columbian times to the present day. and depicting a mushroom strongly resembling Psilocybe mexicana was found in a west Mexican shaft and chamber tomb in the state of Colima.
Over 100 species are classified in the genus Psilocybe.